Clinical Prediction Models

A Practical Approach to Development, Validation, and Updating

af Ewout W. Steyerberg

PrefaceviiAcknowledgementsxi Chapter 1Introduction1 1.1Diagnosis, prognosis and therapy choice in medicine1 1.1.1Predictions for personalized evidence-based medicine1 1.2Statistical modeling for prediction5 1.2.1Model assumptions5 1.2.2Reliability of predictions: aleatory and epistemic uncertainty6 1.2.3Sample size6 1.3Structure of the book81.3.1Part I: Prediction models in medicine8 1.3.2Part II: Developing internally valid prediction models8 1.3.3Part III: Generalizability of prediction models... (Læs mere)